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Biopharma Pulse - 6/27-7/1 Week in Review

As we reach the end of June, we review moves from smid-cap biopharma companies during this past week. See Table 1 for weekly moves and moves YTD for companies and categories on BPIQ.com compared to XBI. To subscribe to BPIQ companies Learn more here.




Table 1. BPIQ company weekly/monthly moves and YTD moves

Category

Weekly Move 6/27-7/1

YTD Move

All BPIQ Companies

​-0.89%

-45.82%

CAR-T Companies

​-1.71%

-53.85%

Gene Editing Companies

​-4.73%

-52.58%

XBI

-0.67%

-31.64%

See the biggest moves from last week below:

 

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Highlights for the week


Biggest positive move



Biggest negative move

  • #TALS -70.92% Talaris Therapeutics Provides FREEDOM-1 Phase 3 Clinical Update



Additional weekly big moves

  • #AXSM +66.2% Axsome Therapeutics Hosts Sunosi® Investor Update Virtual Event Today with Key Opinion Leaders

  • #DBTX +65.5% Decibel Therapeutics Reports Positive Data from Interim Analysis of Ongoing Phase 1b Clinical Trial of DB-020 in Patients Receiving Cisplatin Chemotherapy.

  • #EPZM +55.8% Ipsen to Acquire Epizyme, Expanding Its Portfolio in Oncology. source

  • #ENDP +54.1% Endo Provides Top-Line Results from Phase 2 Study of Collagenase Clostridium Histolyticum (CCH) in Participants with Adhesive Capsulitis of the Shoulder. source

  • #KZR +53.8% Kezar Life Sciences Announces Positive Topline Results from the MISSION Phase 2 Trial Evaluating Zetomipzomib for the Treatment of Patients with Lupus Nephritis.

  • #STRO +21.5% Astellas and Sutro Biopharma Announce Worldwide Strategic Collaboration to Advance Novel Immunostimulatory Antibody-Drug Conjugates (iADCs).

  • #GRAY +19.5% Graybug Announces Review of Strategic Alternatives.

  • #NVAX +10.6% Novavax Statement on Prototype Vaccine’s Broad Immune Responses and Accelerated Focus on Omicron BA.4/5 as Recommended by the FDA. source Galera Announces Results from Phase 1 Stage of GRECO-1 Trial of Rucosopasem with SBRT for NSCLC.

  • #SPRO -11.7% Spero Therapeutics Receives Complete Response Letter from U.S. Food and Drug Administration for Tebipenem HBr New Drug Application

  • #RLAY -13.3% Relay Therapeutics Discloses Anticipated Registrational Path for RLY-4008 in Cholangiocarcinoma and Growing Breast Cancer Franchise at Virtual Analyst and Investor Event.

  • #NUVB -16% Nuvation Bio Announces FDA Partial Clinical Hold for Phase 1 Study of NUV-422 in Solid Tumors.

  • #HRTX -20% Heron Therapeutics Announces Restructuring and Cost Reduction Plan to Address Market Dynamics and Prepare for Long-Term Sustainability.

  • #AMRN -25% REDUCE-IT EXPLORATORY POST HOC BIOMARKER SUB-ANALYSIS SHOWS RELATIVELY SMALL CHANGES IN INFLAMMATORY MARKERS BETWEEN ICOSAPENT ETHYL AND PLACEBO.

  • #ICVX -27.1% Icosavax Announces Positive Topline Interim Phase 1/1b Results for VLP Vaccine Candidate IVX-121 Against RSV.

  • #CDAK -33.7% Codiak Provides Platform-Validating Clinical Update and Data from Phase 1 Trials of exoSTING™ and exoIL-12™.

  • #ALRN -40% Aileron Therapeutics Announces Interim Data from Phase 1b Chemoprotection Trial of ALRN-6924 in Patients with p53-Mutated Non-Small Cell Lung Cancer (NSCLC) and Confirms Development Path for ALRN-6924 Focused on p53-Mutated Breast Cancer.

  • #ENOB -42.0%

  • #NMTR -42.1% 9 Meters Biopharma Announces Positive Preliminary Results from Phase 2 Study of Vurolenatide in Short Bowel Syndrome.

  • #ANGN -42.9% ANGION ANNOUNCES DISCONTINUATION OF PHASE 2 TRIAL OF ANG-3070 IN PATIENTS WITH PRIMARY PROTEINURIC KIDNEY DISEASE

  • #AGRX -44.4% AGILE THERAPEUTICS ANNOUNCES PRICING OF $24 MILLION UPSIZED PUBLIC OFFERING. source





Highlights for next week



See our Big Movers post to learn about upcoming Movers throughout July and PDUFAs, after subscribing. Learn more here.



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